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Eur J Nucl Med. 1993 Jan;20(1):80-2.

Indium-111-labelled antimyosin antibody imaging in a patient with cardiac sarcoidosis.

Author information

1
Institute of Nuclear Medicine, University Hospital, Ruhr-Universit├Ąt Bochum, Bad Oeynhausen, Federal Republic of Germany.

Abstract

The aetiology of cardiac dysfunction caused by sarcoid granulomatous inflammation may be difficult to clarify, and the potential of imaging methods is limited. We report on a patient who presented with acute biventricular decompensation. Pulmonary sarcoidosis was confirmed after hospitalization. Four weeks after the initiation of corticosteroid treatment, scintigraphy with indium-111-labelled antimyosin antibody Fab fragments (AMAB) revealed distinct activity accumulation in major parts of the left ventricular wall (heart-lung ratio: 1.6) 72 h following injection. There may be a role for AMAB scintigraphy in the early detection of cardiac sarcoidosis.

PMID:
8420786
DOI:
10.1007/bf02261250
[Indexed for MEDLINE]

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