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J Comp Pathol. 1993 Jul;109(1):21-7.

Neurotropism of mouse-adapted haemagglutinating encephalomyelitis virus.

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1
Laboratory Animal Research Center, University of Tsukuba, Ibaraki, Japan.

Abstract

The propagation of a mouse-adapted strain (67N) of haemagglutinating encephalomyelitis virus in infected mice and murine cells was examined by viral re-isolation and immunostaining. Viral propagation was strictly limited to the neurons and to an established line of neuroblastoma cells in in-vivo and in-vitro experiments. These results provide adequate evidence that this virus is neurotropic.

PMID:
8408778
[Indexed for MEDLINE]
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