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Curr Opin Neurobiol. 1993 Jun;3(3):375-82.

Calcium waves.

Author information

1
Department of Pharmacology, Physiology and Biophysics, Mayo Foundation, Rochester, MN 55905.

Abstract

Intracellular Ca2+ oscillations and waves are commonly observed both in excitable cells, including neurons, and in non-excitable cells. Current attempts to describe and explain these complex intracellular signals suggest that the oscillations are the result of a highly regulated mechanism, the details of which vary among different cells. Recently, the Xenopus oocyte has become an important model system in which a single pool of IP3 receptors release Ca2+ to initiate waves. The intrinsic bell-shaped dependence of the IP3 receptor on Ca2+ is sufficient to explain the regenerative wave phenomenon.

PMID:
8396478
DOI:
10.1016/0959-4388(93)90131-h
[Indexed for MEDLINE]

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