Format

Send to

Choose Destination
Trends Biochem Sci. 1993 May;18(5):172-7.

On target with a new mechanism for the regulation of protein phosphorylation.

Author information

1
Department of Biochemistry, University of Otago, New Zealand.

Abstract

There is overwhelming evidence that the reversible phosphorylation of proteins regulates most aspects of cell life. However, the broad specificities displayed by many protein phosphatases and kinases in vitro dictates that their activities be strictly regulated in vivo. Recent evidence indicates that a novel class of proteins, known as targetting subunits, specifies the location, catalytic and regulatory properties of protein phosphatases and kinases, and thereby plays a key role in ensuring the fidelity of protein phosphorylation.

PMID:
8392229
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center