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Genomics. 1993 Apr;16(1):254-5.

Characterization of three overlapping deletions causing X-linked lymphoproliferative disease.

Author information

1
Center for Human Genetics, Boston University School of Medicine, Massachusetts.

Abstract

Blot hybridization was used to find DNA sequences missing in a male who lacked two-thirds of Xq25. The probes were used to discover two additional males with deletions resulting in X-linked lymphoproliferative disease (XLP). All three deletions have a region in common, and DXS739 is within this candidate region. The new deletions were also detectable using chromosome banding, and the smallest removes only one-third of Xq25. XLP is the only consequence of the deletions.

PMID:
8387453
DOI:
10.1006/geno.1993.1169
[Indexed for MEDLINE]

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