Format

Send to

Choose Destination
Hematol Oncol Clin North Am. 1993 Apr;7(2):467-75.

Therapy for transplant-related lymphoproliferative diseases.

Author information

1
Pediatric Hematology and Immunology Unit, Hôpital des Enfants-Malades, Paris, France.

Abstract

Epstein-Barr virus can induce an uncontrolled B cell proliferation called B lymphocyte proliferative disorder (BLPD) in immunocompromised hosts. It is a complication that is increasing in prevalence with the growing frequency of transplantation. About 40% of BLPD are reversible following reduction of immunosuppressive therapy. In other instances, BLPD are often fatal with the exception of localized tumors that can be surgically excised. Therapeutic strategies have included antiviral drugs, alpha-interferon, and anti-B cell antibodies.

PMID:
8385662
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center