Format

Send to

Choose Destination
Eur J Pharmacol. 1993 Feb 9;231(2):313-4.

Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent.

Author information

1
Department of Natural Products, Hebrew University, Pharmacy School, Jerusalem, Israel.

Abstract

Anandamide (arachidonylethanolamide) is a brain constituent which binds to the cannabinoid receptor. We now report the first in vivo examination of this ligand. Anandamide administered i.p. in mice, caused lowering of activity in an immobility and in an open field test, and produced hypothermia and analgesia. These effects parallel those caused by psychotropic cannabinoids.

PMID:
8384116
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center