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Life Sci. 1993;52(13):1087-90.

NADP-linked isozymes are the major forms of isocitrate dehydrogenase in mouse type-1-like astrocytes.

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1
Department of Anatomy, University of Saskatchewan, Saskatoon, Canada.

Abstract

The activities of cytosolic NADP-linked and mitochondrial NADP- and NAD-linked isocitrate dehydrogenases were examined in three-week-old mouse astroglial cultures. The respective activities were found to be 57 +/- 7, 101 +/- 3 and 8 +/- 1 nmoles NAD(P)+ reduced per mg protein per min. Both dibutyryl cyclic AMP and cortisol caused a significant increase in the activity of the mitochondrial as well as cytosolic NADP-linked isozymes.

PMID:
8383781
[Indexed for MEDLINE]
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