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Med Clin North Am. 1993 Sep;77(5):1129-48.

Toxic megacolon.

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  • 1Department of Medicine, Mt. Sinai School of Medicine, New York, New York.


Toxic megacolon, its incidence, differential diagnosis, and presenting signs and symptoms are reviewed in this article. The typical histologic and radiographic features are described with a review of the potential triggering factors. An outline of requirements for adequate monitoring of the patient with toxic megacolon is provided. The general management and specific medical management are discussed in detail, and the medical outcome with both medical and surgical intervention is reviewed.

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