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Biochim Biophys Acta. 1993 Sep 13;1144(2):221-4.

Intimate relationships of the large and the small subunits of all nickel hydrogenases with two nuclear-encoded subunits of mitochondrial NADH: ubiquinone oxidoreductase.

Author information

1
E.C. Slater Institute, BioCentrum, University of Amsterdam, The Netherlands.

Abstract

The sequence pattern CxxCxnGxCxxxGxmGCPP, thus far found in the small subunits from 21 different nickel hydrogenases, appears also to be present in the PSST polypeptide from NADH:ubiquinone oxidoreductase (Complex I) of beef-heart mitochondria. There is only one difference: the first cysteine residue is a leucine in the PSST subunit. The large nickel-binding subunit of nickel hydrogenases shows a surprising homology with the 49 kDa subunit of mitochondrial Complex I.

PMID:
8369340
DOI:
10.1016/0005-2728(93)90176-g
[Indexed for MEDLINE]

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