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Chest. 1993 Sep;104(3):955-6.

Localized Wegener's granulomatosis relapsing as diffuse massive intra-alveolar hemorrhage.

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Department of Internal Medicine B, B'nai Zion Medical Center, Haifa, Israel.


In a 75-year-old patient presenting with a solitary pulmonary mass, a localized form of Wegener's granulomatosis was diagnosed after lobectomy. In the absence of extrapulmonary manifestations and after a benign postoperative course, the patients was discharged without medical treatment. Three months later, diffuse alveolar hemorrhage developed abruptly, necessitating mechanical ventilation, and was followed by cardiac complications and a fatal outcome. This case and another previously reported strongly suggest the need for medical treatment in patients with a localized form of pulmonary Wegener's granulomatosis, even when complete remission after surgical resection of the lung lesion seems to have been achieved.

[Indexed for MEDLINE]

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