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Immunol Today. 1993 Jul;14(7):357-62.

Signal transduction events leading to T-cell lymphokine gene expression.

Author information

1
Dept of Medicine, Howard Hughes Medical Institute, University of California, San Francisco 94143.

Abstract

The expression of T-cell derived lymphokines is regulated by signal transduction events initiated by the T-cell antigen receptor and other T-cell surface molecules. Substantial progress has been made in characterizing the signal transduction events initiated at the plasma membrane of the T cell and their targets which control lymphokine gene expression in the nucleus. This review will summarize recent progress in this area of investigation.

PMID:
8363726
DOI:
10.1016/0167-5699(93)90236-E
[Indexed for MEDLINE]

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