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J Nat Prod. 1993 Jun;56(6):921-5.

Bioactive and other sesquiterpenoids from Porella cordeana.

Author information

1
Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg 24061-0212.

Abstract

Bioassay-directed fractionation of the MeCOEt extract of Porella cordeana yielded drimenin [1] and aristolone [4], which were moderately toxic towards DNA-repair-deficient mutants of Saccharomyces cerevisiae. Three inactive sesquiterpenes, 7-ketoisodrimenin [2], 7-ketoisodrimenin-5-ene [3], and norpinguisanolide, were also obtained. Compounds 2 and 3 are new.

PMID:
8350093
[Indexed for MEDLINE]

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