Format

Send to

Choose Destination
Ann Pharmacother. 1993 May;27(5):616-21.

Medication compliance in elderly outpatients using twice-daily dosing and unit-of-use packaging.

Author information

1
Department of Pharmacy Practice, School of Pharmacy, Purdue University, Wishard Memorial Hospital, Indianapolis, IN 46202.

Abstract

OBJECTIVE:

To determine the effect of unit-of-use drug packaging of medications on compliance among elderly outpatients treated with complex medication regimens.

DESIGN:

Nonblind, randomized, clinical trial.

SETTING:

Geriatric outreach health centers in urban public housing units for independent-living elderly people.

PATIENTS:

Thirty-one patients (aged > or = 60 y), each taking three or more prescribed medications. Patients were randomly assigned to one of three study groups: group 1 (n = 12), no change in dosing or packaging; group 2 (n = 10), conventional packaging with twice-daily dosing; group 3 (n = 9), unit-of-use packaging with twice-daily dosing.

INTERVENTION:

A unit-of-use package consisting of a two-ounce plastic cup with a snap-on lid containing all medications to be taken at the time of dosing.

MAIN OUTCOME MEASURES:

Medication compliance was assessed monthly for six months using tablet counts.

RESULTS:

Medication compliance was significantly better in group 3 (92.6 percent) using unit-of-use packaging compared with either group 1 (79 percent) or group 2 (82.6 percent) (p = 0.017). Compliance did not differ between groups 1 and 2.

CONCLUSIONS:

In this small study of elderly outpatients taking three or more medications, unit-of-use packaging and twice-daily dosing improved medication compliance compared with conventional packaging.

PMID:
8347915
DOI:
10.1177/106002809302700517
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center