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Hematol Oncol Clin North Am. 1993 Jun;7(3):547-75.

Role of autologous bone marrow transplantation for patients with acute and chronic leukemias.

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Department of Medicine, and Leukemia, Emory University School of Medicine, Atlanta, Georgia.


Autologous bone marrow transplantation has been increasingly used as effective curative therapy for patients with acute myelocytic leukemia or acute lymphoblastic leukemia who are not candidates for allografting. Its potential role for patients with chronic myelocytic leukemia is considered investigational; however, recent advancements in stem cell separation may make autologous transplantation an attractive alternative for this disease as well. The timing of the autologous transplant and the role of marrow purging are discussed in depth. In addition, post-transplant immune modulation and the use of growth factors and other cytokines following autologous reinfusion are currently being investigated.

[Indexed for MEDLINE]

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