Format

Send to

Choose Destination
Br J Surg. 1993 Jun;80(6):723-4.

Use of desmopressin to prevent bleeding complications in patients treated with aspirin.

Author information

1
Department of Surgery, Karolinska Institute, Danderyd Hospital, Sweden.

Abstract

Aspirin induces a haemorrhagic diathesis that persists for at least 1 week after discontinuation of the drug. The effect of the vasopressin analogue desmopressin was studied in 12 patients treated with aspirin who were undergoing cholecystectomy. Desmopressin was given to six of these patients. There were five postoperative bleeding complications; all occurred in patients who had not received desmopressin (P < 0.05). The bleeding time was prolonged in aspirin-treated patients and normalized by desmopressin (P < 0.05). Desmopressin can be used safely to prevent bleeding induced by aspirin.

PMID:
8330156
DOI:
10.1002/bjs.1800800616
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center