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Gene. 1993 Dec 31;137(2):243-5.

Bacillus subtilis flagellar proteins FliP, FliQ, FliR and FlhB are related to Shigella flexneri virulence factors.

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Department of Biochemistry, Colleges of Liberal Arts and Medicine, University of Illinois, Urbana 61801.


The amino acid sequences of the Bacillus subtilis flagellar proteins, FliP, FliQ, FliR and FlhB, as deduced from their respective nucleotide sequences, were found to share significant homology to the Shigella flexneri Spa24, Spa9, Spa29 and Spa40 virulence proteins, respectively. These proteins are required for the presentation of surface plasmid antigens. These results further support the growing hypothesis that a superfamily of proteins exists for the biosynthesis of supramolecular structures that lie in an external to the cell membrane.

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