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Cytogenet Cell Genet. 1994;66(2):132-4.

Assignment of the human PAX4 gene to chromosome band 7q32 by fluorescence in situ hybridization.

Author information

1
Department of Human Genetics, Nagasaki University School of Medicine, Japan.

Abstract

Of the nine known members of a human paired box-containing gene family (Pax), only PAX4 has not been precisely localized. We screened a cosmid library of human genomic DNA using polymerase chain reaction products for PAX4 as a probe and isolated three positive cosmid clones. Sequence analysis revealed that at least two of them had exon-like sequences and showed extensive homology to Pax-4 in the mouse. These two cosmid clones were mapped to human chromosome band 7q32 by fluorescence in situ hybridization.

PMID:
8287686
DOI:
10.1159/000133684
[Indexed for MEDLINE]

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