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Br J Dermatol. 1993 Dec;129(6):696-9.

Folliculitis in Down's syndrome.

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Department of Dermatology, Bristol Royal Infirmary, U.K.


Twenty-two male and 20 female adults with Down's syndrome were examined. Ten of the men and two of the women had a follicular rash consistent with Malassezia folliculitis. Oral itraconazole treatment produced a significant improvement in the rash, accompanied by a decrease in the skin Malassezia count. Clinical relapse occurred when therapy was discontinued, and was accompanied by return of the Malassezia yeasts.

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