The relationship between endoscopic findings of gastric ulcer scar and ulcer relapse

J Clin Gastroenterol. 1993:17 Suppl 1:S64-9. doi: 10.1097/00004836-199312001-00014.

Abstract

Regenerated mucosal patterns that appeared during the healing of chronic gastric ulcers were observed and assessed in detail by magnifying endoscopes. Three patterns of ulcer scarring were distinguished: Sa with central depression, Sb with a coarse regenerated mucosal pattern, and Sc with a fine mucosal pattern. From a study on the relationship between the depth of ulcer confirmed histologically and the endoscopic findings of the scar, a clear distinction could be made endoscopically between U1-IV scar with a well-demarcated scarring zone, U1-III scar with an unclear boundary, and U1-II scar without a distinct scar area. Scar patterns were also related to ulcer depth. Analysis of the relationship between an ulcer relapse and the scar pattern demonstrated that the ulcer relapse rate over a 2-year follow-up period was 84% in Sa, 33% in Sb, and 0% in Sc.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Famotidine / therapeutic use
  • Female
  • Gastric Mucosa / drug effects
  • Gastric Mucosa / pathology
  • Gastroscopy*
  • Humans
  • Male
  • Middle Aged
  • Omeprazole / therapeutic use
  • Recurrence
  • Stomach Ulcer / drug therapy
  • Stomach Ulcer / pathology*
  • Wound Healing / drug effects
  • Wound Healing / physiology*

Substances

  • Famotidine
  • Omeprazole