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J Appl Physiol (1985). 1993 Oct;75(4):1691-5.

Effect of 8 wk of bicycle training on the immune system of patients with rheumatoid arthritis.

Author information

1
Department of Medicine TTA, Rigshospitalet, Copenhagen, Denmark.

Abstract

The effect of 8 wk of progressive bicycle training on the immune system was evaluated in a controlled study on 18 patients with rheumatoid arthritis and moderate disease activity. Maximal O2 uptake increased significantly, whereas heart rate at stage 2 and rate of perceived exertion decreased significantly, in the training group compared with the controls. Resting levels of a number of immune parameters were measured before and after 4 and 8 wk of training. Training did not induce changes in blood mononuclear cell subpopulations, proliferative response, or natural killer cell activity. Furthermore the plasma concentrations of interleukin-1 alpha, interleukin-1 beta, and interleukin-6 did not change in response to training. It is concluded that 8 wk of bicycle training does not influence the immune system of patients with rheumatoid arthritis.

PMID:
8282621
DOI:
10.1152/jappl.1993.75.4.1691
[Indexed for MEDLINE]

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