Format

Send to

Choose Destination
J Am Geriatr Soc. 1994 Jan;42(1):57-63.

Longitudinal study on oral health in subjects with Alzheimer's disease.

Author information

1
Department of Oral Medicine, Pathology, and Surgery, University of Michigan School of Dentistry, Ann Arbor 48109-1078.

Abstract

OBJECTIVE:

To examine longitudinal oral health changes in unmedicated, generally healthy subjects with Alzheimer's disease (AD) and compare them to age- and gender-matched healthy, unmedicated control subjects.

DESIGN:

Oral health parameters were evaluated over 2 to 3 years and the results compared between subjects with AD and controls.

SETTING:

Clinical Center of the National Institutes of Health, Bethesda, Maryland.

PARTICIPANTS:

Twenty-one community-dwelling subjects with a clinical diagnosis of AD and 21 age- and gender-matched control subjects. Neither population was being treated for any other systemic condition nor taking any prescription medications.

MEASUREMENTS:

Unstimulated and stimulated major salivary gland flow rates were measured, and gingival, periodontal, dental, and oral mucosal tissues assessed.

MAIN RESULTS:

In general, subjects with AD demonstrated decreased salivary flow rates and diminished oral health, but most longitudinal changes in oral health status were not significantly different than controls.

CONCLUSIONS:

Patients with AD are susceptible to a variety of oral health problems, and progression of AD can lead to a deterioration in oral health and function. These patients require aggressive preventive care to maintain function for as long as possible, which necessitates close cooperation among numerous health care professionals.

PMID:
8277117
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley Icon for MLibrary (Deep Blue)
Loading ...
Support Center