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Curr Opin Genet Dev. 1993 Oct;3(5):730-5.

Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome.

Author information

1
Department of Microbiology and Immunology, University of California, San Francisco 94143.

Abstract

The ribosomal DNA locus of Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified cis-acting elements that regulate rDNA processing in the developing macronucleus and subsequent vegetative rDNA maintenance.

PMID:
8274855
DOI:
10.1016/s0959-437x(05)80091-7
[Indexed for MEDLINE]

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