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Biol Pharm Bull. 1993 Sep;16(9):930-1.

Anti-tumor promoting activities of natural products. II. Inhibitory effects of digitoxin on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors.

Author information

1
Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan.

Abstract

Two-stage carcinogenesis of mouse skin papillomas induced by 7,12-dimethylbenz[a]anthracene (DMBA) and 12-O-tetradecanoylphorbol-13-acetate (TPA), and mouse pulmonary tumors induced by 4-nitroquinoline-N-oxide (4NQO) and glycerol, were inhibited by digitoxin (1).

PMID:
8268862
DOI:
10.1248/bpb.16.930
[Indexed for MEDLINE]

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