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Trans R Soc Trop Med Hyg. 1993 Sep-Oct;87(5):576-7.

Short course albendazole treatment for neurocysticercosis in Columbia.

Author information

1
School of Medicine and University Hospital, Universidad de Antioquia, Medellin, Colombia.

Abstract

The efficacy of albendazole was evaluated in 20 Colombian patients with neurocysticercosis showing neurological symptoms. All had parenchymal non-enhancing cystic images by computerized tomography and a positive enzyme-linked immunosorbent assay for cysticercus antibodies in serum or cerebrospinal fluid. They stayed in hospital for 8 d during treatment with albendazole, 15 mg/kg/d in 2 divided doses, and were then followed for at least 6 months after treatment. The number of cysts was reduced by 50% after 6 months. In 7 (35%) all cysts disappeared, in 7 (35%) the number was reduced, and in the remaining 6 (30%) the number was unchanged. In the 13 patients who still had cysts at 6 months, 11 showed a moderate decrease in average cyst size and in 2 the size was unchanged. Side effects during treatment were observed in 60% of the cases, but only 3 required corticosteroids.

PMID:
8266415
DOI:
10.1016/0035-9203(93)90095-8
[Indexed for MEDLINE]

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