Send to

Choose Destination
Am J Cardiol. 1993 Aug 26;72(6):23B-25B.

Measurement of the QT interval and the risk associated with QTc interval prolongation: a review.

Author information

Department of Preventive and Community Medicine, University of Rochester School of Medicine and Dentistry, New York.


The accurate measurement of the QT interval and its correction or adjustment for cycle length, age, and gender have been topics of increasing interest over the course of the past 70 years. The availability of digitized electrocardiographic recordings on large normal populations together with statistical adjustment for pertinent covariates has provided useful data for defining QT interval prolongation. Data from the International Long QT Syndrome Registry indicate that the probabilistic risk of developing malignant arrhythmias in patients with QT prolongation is exponentially related to the length of the QTc interval. The risk is further accentuated by the development of T-wave alternans, particularly at very prolonged QTc intervals.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center