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J Affect Disord. 1993 Sep;29(1):49-52.

Anxious and non-anxious bipolar disorder.

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  • 1Mood Disorders Program, Clarke Institute of Psychiatry, Toronto, Canada.


Eighty-one outpatients with bipolar disorder (BD) were grouped by SADS anxiety symptom scores (high vs. low) or diagnosis of generalized anxiety disorder, and/or panic disorder. BD patients with high anxiety scores were more likely to have suicidal behaviour (44% vs. 19%), alcohol abuse (28% vs. 6%), cyclothymia (44% vs. 21%) and an anxiety disorder (56% vs. 25%) with a trend toward lithium non-responsiveness. Diagnosis of an anxiety disorder was related only to high anxiety and lower GAS scores. Thus, anxiety may have similar clinical relevance in BD as it does in unipolar patients.

[PubMed - indexed for MEDLINE]
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