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Vision Res. 1993 Dec;33(17):2431-5.

Comparison of the waveforms of the ON bipolar neuron and the b-wave of the electroretinogram.

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Department of Biophysical Sciences, SUNY School of Medicine, Buffalo 14214.


The b-wave of the electroretinogram (ERG) is believed to result largely from the light responses of ON bipolar neurons. One apparent inconsistency is that the b-wave is a phasic signal, more similar to ON responses of transient third-order neurons than to the ON bipolar light responses. However, when selective glutamate agonists or antagonists were used to isolate the b-wave, it was found to be tonic and resemble the light response waveform of the ON bipolar cell.

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