Hyperactivity and spelling disability: testing for shared genetic aetiology

J Child Psychol Psychiatry. 1993 Oct;34(7):1137-52. doi: 10.1111/j.1469-7610.1993.tb01779.x.

Abstract

The influence of genetic factors in the comorbidity of spelling disability and hyperactivity was investigated in two samples of 190 and 260 same sex twin pairs. The method of bivariate group heritability was used to estimate the genetic correlation for spelling disability and hyperactivity. A similar though not statistically significant value for the genetic correlation was obtained for the two samples (0.29 and 0.42). It was estimated that approximately 75% of the co-occurrence of these two conditions was due to shared genetic influences.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Attention Deficit Disorder with Hyperactivity / diagnosis
  • Attention Deficit Disorder with Hyperactivity / genetics*
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Child
  • Colorado
  • Comorbidity
  • Cross-Cultural Comparison
  • Diseases in Twins / genetics*
  • Diseases in Twins / psychology
  • Female
  • Genetic Markers / genetics
  • Humans
  • Learning Disabilities / diagnosis
  • Learning Disabilities / genetics*
  • Learning Disabilities / psychology
  • London
  • Male
  • Twins, Dizygotic / genetics
  • Twins, Dizygotic / psychology
  • Twins, Monozygotic / genetics
  • Twins, Monozygotic / psychology
  • Verbal Learning*

Substances

  • Genetic Markers