Send to

Choose Destination
FEMS Microbiol Lett. 1993 Oct 1;113(1):87-92.

Towards a phylogeny of the clostridia based on 16S rRNA sequences.

Author information

Department of Microbiology, AFRC Institute of Food Research, Reading Laboratory, UK.


The 16S rRNA sequences of 17 species of the genus Clostridium were determined by direct sequencing of their PCR amplified genes. The sequences were aligned with those from other known clostridial species and representative low G + C Gram-positive relatives, and a phylogenetic tree was constructed. It was evident from the comparative sequence analysis that the genus Clostridium as presently constituted is phylogenetically extremely heterogeneous. This study corroborates and extends earlier findings in showing that many non-sporeforming bacteria are phylogenetically closely intermixed with Clostridium species. The taxonomic implications of the phylogenetic findings are discussed.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center