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Biochim Biophys Acta. 1993 Nov 16;1216(2):289-92.

Structure of the human progesterone receptor gene.

Author information

1
CHU de Bicêtre-3ème niveau, INSERM U135, Hôpital de Bicêtre, France.

Abstract

The complete organization of the human progesterone receptor (hPR) gene has been determined. It spans over 90 kbp and contains eight exons. The first exon encodes the N-terminal part of the receptor. The DNA binding domain is encoded by two exons, each exon corresponding to one zinc finger. The steroid binding domain is encoded by five exons. The nucleotide sequence of 1144 bp of the 5' flanking region has been determined.

PMID:
8241270
DOI:
10.1016/0167-4781(93)90156-8
[Indexed for MEDLINE]

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