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Am J Emerg Med. 1993 Nov;11(6):573-5.

Ketorolac as a rapid and effective treatment of migraine headache: evaluations by patients.

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Department of Surgery (Emergency Services), University of Texas Medical Branch, Galveston 77555.


The objective of this study was to determine the speed and efficiency of ketorolac in reducing the symptoms of migraine headache. Twenty-three patients who presented in the emergency department during the period between April and July 1992 with a previous diagnosis of migraine headache were considered for the study. Patients subjectively evaluated parameters of their migraine headaches (eg, pain and nausea) with a numerical scale and were asked to re-evaluate these same parameters at 30, 60, and 360 minutes after a single injection of Ketorolac. Seventeen (74%) patients reported a decrease in headache symptoms that was significant (P < .005) after 1 hour. Relief lasted at least 6 hours after injection.

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