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Ukr Biokhim Zh (1978). 1993 Mar-Apr;65(2):89-94.

[Influence of ethanol and ethanol-induced lipid peroxidation on the steroidogenic activity of testicles].

[Article in Russian]

Abstract

Chronic alcohol intoxication results in the diminished testosterone level and activation of lipid peroxidation in rat testes. A significant decrease in 3 beta-hydroxysteroid-hydrogenase and 17-dehydrogenase activity has been observed in microsomes. Analogous shifts have been evoked in vitro by the induction of lipid peroxidation in microsomes. That permitted one to suppose that alcohol-induced alterations in tests are partially mediated by induction of lipid peroxidation.

PMID:
8236538
[Indexed for MEDLINE]

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