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Neuropediatrics. 1993 Aug;24(4):230-1.

Vigabatrin in the treatment of infantile spasms.

Author information

1
Department of Child Neurology, University Hospital Maastricht, The Netherlands.

Abstract

The anti-epileptic effect of vigabatrin as a first choice therapy was investigated in 6 children suffering from infantile spasms (IS). All 6 children showed a reduction in seizure frequency. Three children became seizure-free within a period of 2 weeks. Because our results suggest "an all or nothing phenomenon", a period of 2 weeks may be sufficient to evaluate the efficacy of vigabatrin in untreated infants suffering from IS. We suggest to use vigabatrin as a first choice anti-epileptic drug in infants with IS.

PMID:
8232783
DOI:
10.1055/s-2008-1071546
[Indexed for MEDLINE]

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