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Med Hypotheses. 1993 Aug;41(2):131-3.

Possible reversal of ageing and other mitochondrial deficiencies through retroviral transfection of mitochondrially encoded proteins to the nucleus.

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1
School of Life Science, Queensland University of Technology, Brisbane, Australia.

Abstract

This paper puts forward the hypothesis that ageing processes and a number of mitochondrially related diseases can be reversed or cured respectively. It briefly discusses the role of the mitochondrial genome in ageing and a number of inherited and age-related diseases. A rationale is then suggested which involves the utilization of retroviruses in translocating mitochondrial encoded proteins to the nucleus. Finally a number of problems which may arise from this translocation are discussed.

PMID:
8231991
[Indexed for MEDLINE]

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