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Int J Epidemiol. 1993 Aug;22(4):742-6.

Estimation of vaccine effectiveness using the screening method.

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  • 1PHLS Communicable Disease Surveillance Centre, London, UK.


The screening method provides a simple and rapid way of estimating vaccine effectiveness. The paper discusses the validity of the screening method with particular reference to bias and precision. Methods for correcting confounding, adjusting for covariates and over-dispersion, and deriving confidence limits are discussed in a modelling framework. The methods are illustrated using data on measles and pertussis vaccines.

[PubMed - indexed for MEDLINE]
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