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Gastrointest Endosc. 1993 Sep-Oct;39(5):670-3.

Bacterial adherence to hydrophilic polymer-coated polyurethane stents.

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Institute of Medical Microbiology and Hygiene, University of Cologne, Germany.


Biliary stent blockage by adherence of bacteria and formation of biofilm is a major problem in endoscopic stenting procedures. We have investigated bacterial adherence to hydrophilic polymer (Hydromer)-coated polyurethane stents in stationary and perfusion experiments. Adherence of gram negative and gram positive organisms under stationary conditions was similar between Hydromer-coated and non-coated control polyurethane stents; however, a marked 1 to 3 log reduction in adherence to Hydromer-coated stents occurred when perfusion experiments in phosphate buffer solution or bile were performed. The results suggest that Hydromer-coated polyurethane stents could be useful in preventing complications caused by biliary stent blockage.

[Indexed for MEDLINE]

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