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J Comput Assist Tomogr. 1994 May-Jun;18(3):432-8.

CT and MR distinction of adenomas and nonadenomas of the adrenal gland.

Author information

1
Department of Diagnostic Radiology and Nuclear Medicine, Leiden University Hospital, The Netherlands.

Abstract

OBJECTIVE:

Because the distinction between adenomas and nonadenomas of the adrenal gland is essential, we investigated which of the following parameters--size, CT attenuation values, MRI signal intensity ratios on T1- and T2-weighted sequences, calculated T2 relaxation times, or T2 relaxation time ratios--provides better discrimination.

MATERIALS AND METHODS:

We compared these parameters in 44 adrenal masses of 37 patients by means of the Student t test and receiver operating characteristics (ROC) analyses.

RESULTS:

Only size, CT attenuation values, and signal intensity ratios on T2-weighted MR images of adenomas showed a significant difference from those of nonadenomas. With use of ROC analysis, CT demonstrated a significantly larger area under the curve compared to size and T2 signal intensity ratios, indicating superior performance.

CONCLUSION:

We found attenuation values on non-contrast-enhanced CT to be the best method in discriminating adrenal adenomas from nonadenomas. Adrenal masses with CT attenuation values below 15 HU warrant no further investigations.

[Indexed for MEDLINE]

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