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Cardiovasc Intervent Radiol. 1994 Jan-Feb;17(1):12-6.

Prophylactic endovascular radiotherapy to prevent intimal hyperplasia after stent implantation in femoropopliteal arteries.

Author information

1
Department of Radiology, J.W. Goethe University Hospital, Frankfurt am Main, Germany.

Abstract

PURPOSE:

Recurrent stenosis or occlusion by intimal hyperplasia occurs in up to 40% of patients with tantalum stent implantations in femoropopliteal arteries and greatly restricts their usefulness. We evaluated the effect of prophylactic endovascular radiotherapy on stenosed/occluded stents.

METHODS:

We investigated prophylactic endovascular radiotherapy with a surface dose of 12 Gy using an iridium 192 source as a means to reduce or eliminate recurrent stenosis in 4 patients with stenosed/occluded stents, 6-8 months after the original implantation. Confirmatory diagnostic atherectomy, PTA or laser recanalization and endovascular radiotherapy were performed.

RESULTS:

None of the four has developed recurrent obstruction within 23 to 30 months after this treatment, which up to now shows no short-term or long-term complications.

CONCLUSION:

We conclude that this limited experience is promising enough to warrant further study.

PMID:
8187126
[Indexed for MEDLINE]

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