Comparison of continuous infusions and bolus injections of 5-fluorouracil with or without leucovorin: implications for inhibition of thymidylate synthase

Adv Exp Med Biol. 1993:339:9-20; discussion 21. doi: 10.1007/978-1-4615-2488-5_2.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Colonic Neoplasms / blood
  • Colonic Neoplasms / drug therapy*
  • Fluorouracil / administration & dosage*
  • Fluorouracil / pharmacokinetics
  • Fluorouracil / toxicity
  • Infusions, Parenteral
  • Injections, Intraperitoneal
  • Leucovorin / administration & dosage*
  • Mice
  • Thymidylate Synthase / antagonists & inhibitors*

Substances

  • Thymidylate Synthase
  • Leucovorin
  • Fluorouracil