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Curr Opin Neurobiol. 1994 Feb;4(1):108-11.

Cortical development and topographic maps: patterns of cell dispersion in developing cerebral cortex.

Author information

1
Alzheimer Research Lab, Case Western Reserve Medical School, Cleveland, Ohio 44106.

Abstract

Cortical neurons are organized into highly patterned ensembles of cells, each with a distinct physiological function. The precursors of these cells arise in the ventricular zone, itself a highly patterned mosaic of cells. To determine whether the ventricular pattern presages the adult, investigators examine the process of cell migration. Recent evidence suggests that both radial (pattern-preserving) and tangential (pattern-blurring) cell movements occur during development.

PMID:
8173316
DOI:
10.1016/0959-4388(94)90039-6
[Indexed for MEDLINE]

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