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Immunol Today. 1994 Mar;15(3):121-6.

Complement factor H and related proteins: an expanding family of complement-regulatory proteins?

Author information

1
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

Abstract

Recently, several factor-H-related molecules have been identified in humans and mice, initiating new interest in this group of serum proteins. Although no complement-regulatory activity has been demonstrated yet for the human factor-H-related proteins, the immunological and structural similarities to factor H suggest overlapping functions. Here, Peter Zipfel and Christine Skerka review these similarities and suggest a new nomenclature to identify members of the factor-H-related family.

PMID:
8172644
DOI:
10.1016/0167-5699(94)90155-4
[Indexed for MEDLINE]

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