Format

Send to

Choose Destination
J Med Primatol. 1993 Sep-Oct;22(7-8):433-4.

Lack of susceptibility of various primates and woodchucks to hepatitis C virus.

Author information

1
Department of Pathology, National Institute of Health, Tokyo, Japan.

Abstract

Five different species of primates including cynomolgus monkey, rhesus monkey, green monkey, Japanese monkey, and doguera baboon and woodchucks were inoculated intravenously with infectious serum from a chimpanzee infected with hepatitis C. Serum samples obtained weekly from these animals were negative for hepatitis C virus RNA and anti-HCV during six months following inoculation. Furthermore, serum alanine aminotransferase remained within normal limits, and normal liver histology was seen. This study indicates that these primates and woodchucks do not appear to be susceptible to hepatitis C virus.

PMID:
8169947
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center