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Trends Microbiol. 1994 Feb;2(2):52-6.

Mechanisms of virus uncoating.

Author information

1
Dept of Cell Biology, Yale University School of Medicine, New Haven, CT 06520.

Abstract

In a virus particle, the genome is highly condensed and protected by proteins and membrane bilayers. Before it can be replicated in a new host cell, uncoating must take place. Recent studies on enveloped and nonenveloped animal viruses indicate that uncoating occurs through complex, multistep processes triggered by virus-host-cell interactions.

PMID:
8162442
DOI:
10.1016/0966-842x(94)90126-0
[Indexed for MEDLINE]
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