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Trends Microbiol. 1994 Mar;2(3):76-81.

Short-sighted evolution and the virulence of pathogenic microorganisms.

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Dept of Biology, Emory University, Atlanta, GA 30322.


For some microorganisms, virulence may be an inadvertent consequence of mutation and selection in the parasite population, occurring within a host during the course of an infection. This type of virulence is short-sighted, in that it engenders no advantage to the pathogen beyond the afflicted host. Bacterial meningitis, poliomyelitis and AIDS are three candidates for this model of the evolution of virulence.

[Indexed for MEDLINE]

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