Format

Send to

Choose Destination
Int Arch Allergy Immunol. 1994;104 Suppl 1(1):63-4.

A review on Fc epsilon RI on human epidermal Langerhans cells.

Author information

1
Department of Internal Medicine, Sakura Hospital, Toho University, School of Medicine, Japan.

Abstract

In order to show the surface expression of Fc epsilon RI on human epidermal Langerhans cells (LC), we examined monomeric IgE binding to LC. We demonstrated that the majority of epidermal LC were able to bind monomeric IgE. IgE binding to LC could neither be prevented by preincubation of the tissue with monoclonal antibodies (mAb) against either Fc epsilon RII/CD23 or Fc gamma RII/CD32, nor by the addition of lactose, but could be entirely abrogated by preincubation with the anti-Fc epsilon RI mAb 15-1. These data show that epidermal LC express Fc epsilon RI molecules.

PMID:
8156009
DOI:
10.1159/000236756
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for S. Karger AG, Basel, Switzerland
Loading ...
Support Center