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Immunol Today. 1994 Feb;15(2):81-8.

The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein.

Author information

1
Dept of Genetics, Trinity College, University of Dublin, Ireland.

Abstract

Following an acute phase stimulus, such as infection or physical injury, many liver-derived plasma proteins are increased in concentration. These provide enhanced protection against invading micro-organisms, limit tissue damage and promote a rapid return to homeostasis. Diana Steel and Alexander Whitehead discuss the gene structure, regulation and possible clinical significance of the most dramatically induced acute phase reactants.

PMID:
8155266
DOI:
10.1016/0167-5699(94)90138-4
[Indexed for MEDLINE]

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