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Trends Microbiol. 1993 Apr;1(1):25-31.

The wily ways of a parasite: induction of actin assembly by Listeria.

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Dept of Biology, University of Pennsylvania, Philadelphia 19104-6018.


The intracellular pathogen Listeria has a spectacular mode of transport within and between host cells. By inducing host cell actin to assemble from its surface, the bacterium forms a tail composed of many short, crossbridged actin filaments. With this tail Listeria is propelled across the cytoplasm like a comet streaking across the sky. Here we discuss the antics of Listeria and some of the bacterial genes instrumental in maintaining it in the host.

[Indexed for MEDLINE]

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