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Cornea. 1994 Jan;13(1):73-7.

Recurrent keratoconus.

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Eye Pathology Laboratory, Johns Hopkins University School of Medicine, Baltimore, Maryland.


Keratoconus is a progressive, noninflammatory, nonvascular axial corneal ectasia, with unclear etiology and pathogenesis. It has a prevalence of 50-230 per 100,000 and is a bilateral disorder in up to 90% of cases. The onset of keratoconus is usually at puberty and progresses over 10-20 years producing an irregular myopic astigmatism. The treatment depends on the severity of the irregular astigmatism. Advanced keratoconus, which cannot be treated with contact lenses, requires a surgical procedure--either penetrating keratoplasty, epikeratophakia, or thermokeratoplasty. The results of penetrating keratoplasty are good, with success rates of > 90% of the cases. Recurrence of keratoconus following penetrating keratoplasty has been previously reported, based on a clinical diagnosis, and confirmed by histopathological examination. We report the clinicopathologic features of two further cases of recurrent keratoconus.

[Indexed for MEDLINE]

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