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Obstet Gynecol. 1994 Mar;83(3):357-61.

Risk factors for severe preeclampsia.

Author information

1
Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai Medical Center, New York, New York.

Abstract

OBJECTIVE:

To identify risk factors associated with severe preeclampsia and to determine whether these factors are similar in nulliparous and multiparous patients.

METHODS:

Patients whose pregnancies were complicated by severe preeclampsia (n = 70) were compared retrospectively to 18,964 non-preeclamptic controls. Information on maternal demographic factors; medical, obstetric, and family histories; and neonatal outcome was retrieved and analyzed by univariate and multivariate analysis.

RESULTS:

By logistic regression, the only risk factors associated with the development of severe preeclampsia were severe obesity in all patients (adjusted odds ratio 3.5, 95% confidence interval [CI] 1.68-7.46) and a history of preeclampsia in multiparous patients (adjusted odds ratio 7.2, 95% CI 2.74-18.74).

CONCLUSION:

Severe obesity and a history of preeclampsia are the only maternal risk factors identified for the development of severe preeclampsia.

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PMID:
8127525
[Indexed for MEDLINE]

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